Obama campaign spokesman Bill Burton said of the ad, "It is shameful and downright perverse for the McCain campaign to use a bill that was written to protect young children from sexual predators as a recycled and discredited political attack against a father of two young girls - a position that his friend Mitt Romney also holds. Last week, John McCain told Time magazine he couldn't define what honor was. Now we know why."
More via The Huffington Post on what the articles cited in the ad had to say about McCain.
Update: Planned Parenthood comes to Obama's defense.